Across the domains of life, transcription factors play pivotal roles in enabling cells to respond to external cues with specialized and genetically encoded gene expression programs. The Kim Lab at UC Irvine is decoding how transcription factors work in a combinatorial and quantitative manner to define cell states and transitions among them during mammalian development. We combine high-throughput cellular genetics in stem cell models with detailed molecular analysis and computational genomics approaches. Learn more.
Kim Lab at UC Irvine 